Mr. Huff is the Founder, Chairman, and Chief Executive Officer of Reata Pharmaceuticals, Inc. Founded in 2002, Reata is a biopharmaceutical company focused on selecting and discovering promising early drug development opportunities and translating them into successful marketed drugs that target major unmet clinical needs in cancer, inflammation and neurodegenerative disease. The company’s two lead programs are entering advanced clinical trials for deadly, late-stage cancers. In parallel with its clinical development, Reata is advancing a breakthrough drug discovery platform using protein misfolding, identified as a key factor in cancer and neurodegenerative disease, to feed its pipeline of small molecule therapeutic candidates.

Mr. Huff started his career as an attorney with Johnson & Gibbs, P.C., a large institutional law firm, where he was a Senior Partner and Chairman of the Corporate Securities Practice. Mr. Huff’s practice emphasis included representing issuers, underwriters, and investors in financing and related transactions for companies in the life science, computer, and telecommunications industries.

Mr. Huff left the practice of law to join Ergo Science Corporation, a startup biopharmaceutical company in Boston, Massachusetts. Ergo developed neurotransmitter modulating drugs that were used for the treatment of Type II diabeties. Mr. Huff joined Ergo as its first business executive and served as its President and Chief Executive Officer. Under Mr. Huff’s leadership, Ergo developed a small molecule drug through Phase III clinical trials and NDA filing and completed an initial public offering with leading biotech underwriters within 39 months of its seed financing.

Prior to founding Reata, Mr. Huff served as an entrepreneur in residence at StarTech Ventures and as interim Chief Executive Officer of Light Biology, a developer of customizable DNA microarray systems. Light Biology was combined with NimbleGen Systems, and the combined entity was acquired by Roche Diagnostics in a transaction valued at more than $250.0 million.

Mr. Huff attended Southern Methodist University School of Law and received his Juris Doctor in May 1979. Mr. Huff also attended the University of Texas at Austin and received his Bachelors of Business Administration magna cum laude in May 1976.